Round 10 of the segment includes A-listers Kate Hudson, Melissa McCarthy, Olivia Wilde, Russell Crowe and Zac Effron.
Kicking it off in fine British style was Bridget Jones Diary star, Hugh Grant.
"Watching Hugh Grant and his stuttering pathetic 'charm' is about as appealing to me as closing my scrotum in a DVD case," the British star reads off his phone.
"Are these real or do you make them up to be especially nasty," Hugh then asks someone off-screen, feigning mock surprise at the message.
From the bizarre to the hilarious, the stars read out their mean tweets with plenty of good humour, and most do their best not to crack up at what the trolls have written.
Best comeback goes to Ryan Gosling, who was trolled about his face looking like it was holding in a fart.
Check out the hilarious clip above.